With appearing more evidences for intralipid different applications there is a hope that many types of drug-induced CNS or cardiac toxicities could be treated by Lipid Rescue effect as a safe treatment option. Reportedly lipid infusion was successful in reversing neurological signs of toxicity from local anesthetics. The first case report of successful Lipid Rescue was published in 2006. Weinberg began working on the effects of local anesthetics and discovered that an infusion of lipid emulsion not only protect against but also correct local anesthetic cardiac toxicity. In recent papers many different applications of Intralipid or oil containing products-Lipid Emulsion-have successfully experimented in critical care patients. Intravenous lipid emulsion therapy was introduced as a treatment for local anesthetic toxicity it has shown couple of reversing and therapeutic efficacies for a number of different drug toxicities.
